How insulin was first isolated to treat diabetes

In 1921, Clinician Dr. Federick Banting had a failing medical practice and a burning desire to do research, but had no formal training.  He became fascinated with the role of insulin and the pancreas in diabetics.  One night he had an epiphany on how to isolate insulin-producing islets from the pancreas.  Armed with no credentials, he was able to convince Professor John Macleod to let him use his lab space and one of his medical students to test his theory.  Incredibly, within a few months they were able to revive a dog from diabetic coma.  Several months later they were successfully treating human patients.  Within two years of walking into a lab for the first time, Dr. Banting was awarded the Nobel Prize in Medicine and controversially so was Dr. Macleod who Banting did not think deserved credit.  The choice to award Macleod is still a topic of disagreement today.
Nobel Prize article and image credit

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