In this paper, they use a mouse model to study obesity, insulin sensitivity and exosomal RNA. Basically, they inject extracellular vesicles, or exosomes, from a lean mouse into an obese mouse with insulin sensitivity problems and the impairments are reversed. Exosomes from the obese mice into the lean mice cause insulin resistance. Will this also work as a potential future therapeutic for humans?
- http://www.cell.com/cell/fulltext/S0092-8674(17)30993-5 <-- The paper
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